Dr Christopher Ng
Consultant Obstetrician & Gynaecologist
MBBS (Imperial College, UK), MMed (O&G) (S’pore), FRANZCOG (Aust-NZ), FAMS (O&G) (S’pore)
Oocyte cryopreservation, also called egg freezing, is a way for women to preserve their fertility. It involves extracting, freezing, and storing their eggs (oocytes). It is an increasingly popular option for women who want to delay childbirth (elective/social egg freezing) for various reasons, or preserve their fertility for medical reasons (medical egg freezing). Medical egg freezing is typically used when a woman has been diagnosed with cancer or another medical condition that may affect her fertility. In these cases, egg freezing can help preserve her fertility so that she may still have the opportunity to become pregnant in the future. On the other hand, elective egg freezing is done for non-medical reasons, such as delaying starting a family due to career or lifestyle choices.
While egg freezing does not guarantee a successful pregnancy, it can give women more control over their reproductive health and timeline. Here are some common reasons why some women consider egg freezing:
Many women choose to freeze their eggs in order to delay childbearing. This could be due to career or educational goals that they want to pursue before starting a family, or simply because they are still not mentally or financially prepared for the responsibility of having children. As women's fertility naturally declines with age, egg freezing provides them the opportunity to put off having children until they feel ready to do so.
Egg freezing can reduce stress and anxiety associated with trying to conceive later in life when fertility has decreased significantly. Knowing that you have healthy eggs stored away can provide peace of mind to focus on other aspects of your life without constantly worrying about your reproductive health and feeling like you are racing against time.
Egg freezing can also be used as a way for women with fertility issues to increase their chances of conceiving later on. Women who have been diagnosed with cancer may choose to freeze their eggs before undergoing chemotherapy or radiation treatments, which can cause infertility. Egg freezing can also be used by women who may be starting to experience premature ovarian failure or other conditions that affect fertility.
By storing multiple healthy eggs earlier on, egg freezing can improve the chances of a successful pregnancy later on when the woman is ready for it because the risk of miscarriage and chromosomal abnormalities is lower with decreasing maternal age. The frozen eggs are carefully thawed and fertilized in a laboratory before being implanted into the uterus, increasing the chances that one or more embryos will successfully implant and result in a successful pregnancy.
The egg freezing process begins with hormone injections to stimulate the ovaries to produce multiple eggs. Once the eggs have matured, they are retrieved transvaginally through a minor surgical procedure called oocyte pick up (OPU). The eggs are then inspected by an embryologist and only the viable healthy ones are frozen using a special technique called vitrification. The frozen eggs can then be stored indefinitely until the patient is ready to use them.
When the patient is ready to use her frozen eggs, they will be thawed and fertilized with sperm in a laboratory setting to create embryos. These embryos can then be transferred into the uterus where implantation may occur resulting in pregnancy. It is important to note that while egg freezing allows women to preserve their fertility, it does not always guarantee a successful pregnancy.
Egg freezing in Singapore has become a popular topic of discussion in recent years as women increasingly explore options to preserve their fertility. As the egg freezing process in Singapore is subject to certain restrictions and regulations, here are some to take note of:
Up until recently, egg freezing in Singapore was only permitted for medical reasons, such as prior to undergoing cancer treatment, which can adversely affect one’s fertility; or if one has a family history of early menopause. Previously, women who wished to undergo the procedure for elective or social reasons, such as delaying childbirth for personal reasons, were not allowed to do so. However, it has recently been legalised that women – including single women – can choose to do elective egg freezing in Singapore.
In May 2023, Singapore raised its age limit for elective egg freezing from 35 to 37 in order to allow more women access to the service. It is capped at 37 years old as the quality of eggs have been found to decline substantially after this age.
The probability of successful egg freezing is influenced by various factors, such as:
Age is one of the most important factors in determining egg freezing success rates. Younger women are more likely to have successful pregnancies from frozen eggs than older women.
Generally speaking, women under the age of 35 have an approximately 18% chance of having a baby when five eggs are frozen, while those over the age of 35 only have an approximately 7% chance. Hence, it is very important for women considering egg freezing to do so earlier if possible.
The number of eggs frozen also affects egg freezing success rates. The more eggs a woman has frozen, the more embryos there will be to potentially transfer to the woman’s uterus, and hence the higher her chances of achieving a successful pregnancy. It would be good to freeze at least 20 eggs if possible in order to give patients a realistic chance of completing their family in the future.
However, it is important to note that there is no guarantee that all frozen eggs will be viable – some may not survive the freezing, thawing or fertilization processes.
Other factors that can affect egg freezing success rates include how well they were preserved during storage. Different egg freezing clinics and hospitals may have different standards and equipment for preserving and handling frozen eggs, which can affect outcomes. Patients need to research the facility’s resources and track record carefully before deciding where they will freeze their eggs.
As with all medical procedures, there are some risks involved. With egg freezing, risks may include ovarian hyperstimulation syndrome (OHSS), infection, as well as bleeding and damage to the ovaries or uterus. However, the chances of these happening are rare in the hands of a gynaecologist well versed in egg freezing procedures.
Additionally, there is no guarantee that the eggs will survive the thawing process or result in a successful pregnancy.
It is also important to consider the cost of egg freezing. The procedure can be expensive and may not be covered by insurance. Additionally, storage fees for frozen eggs can add up over time and should be considered when deciding where to freeze one’s eggs and the duration one wishes to freeze their eggs for.
Factors determining the cost of egg freezing include: the number of eggs retrieved, the number of egg retrieval cycles one has undergone, as well as annual storage fees for the frozen eggs.
At private clinics and hospitals, the average cost per egg retrieval cycle can range from around $10,000 to $15,000 on average; with an annual storage charge of approximately $900.
Finally, when the time comes to use the eggs, one will also have to factor in the cost of in-vitro fertilisation (IVF) as the thawed eggs will have to be fertilized with sperm in the fertility centre. The resulting embryos will then be transferred into the woman’s uterus in hope of achieving a successful implantation and pregnancy.
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Dr Christopher Ng
Consultant Obstetrician & Gynaecologist in Singapore
Qualifications & Credentials
Dr Christopher Ng is a dedicated obstetrician and gynaecologist with over two decades of experience. Having been educated and trained in Singapore, the UK and the US, Dr Ng brings with him a wealth of experience and medical knowledge that puts his patient’s wellbeing to the fore.
Dr Ng also complements his practice with aesthetics and has obtained Certificates of Competence in all aesthetic procedures recognised by the Singapore Medical Council Aesthetic Practice Oversight Committee.
With over 30 years of dedicated service in the field of women’s health and rejuvenation, Dr Ng remains steadfast in his commitment to provide compassionate, personalised and effective care to all his patients.
Dr Christopher Ng is a dedicated obstetrician and gynaecologist with over two decades of experience. Having been educated and trained in Singapore, the UK and the US, Dr Ng brings with him a wealth of experience and medical knowledge that puts his patient’s wellbeing to the fore.
Dr Ng also complements his practice with aesthetics and has obtained Certificates of Competence in all aesthetic procedures recognised by the Singapore Medical Council Aesthetic Practice Oversight Committee.
With over 30 years of dedicated service in the field of women’s health and rejuvenation, Dr Ng remains steadfast in his commitment to provide compassionate, personalised and effective care to all his patients.
Phone:+65 6733 8810
Fax:+65 6733 8850
After Office:+65 6535 8833
Email:gynaemd@singnet.com.sg
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